产品英文名称：PeproTech 100-18B Recombinant Human FGF-basic,50ug
产品中文名称：PeproTech 100-18B 人重组bFGF干细胞生长因子,50ug
PeproTech 100-18B Recombinant Human FGF-basic,50ug 产品简介
FGF-basic 又称FGF-2, HBGF-2, Prostatropin，它是23种已知FGF家族成员之一。FGF家族蛋白在胚胎发育和胚后生长及组织再生方面发挥重要作用，可促进细胞增殖和分化。FGF-basic是一个非糖基化肝素结合生长因子，在脑、垂体、肾、视网膜、骨、睾丸、肾上腺肝、单核细胞、薄壁分泌细胞和内皮细胞中表达。FGF-basic通过FGFR 1b, 1c, 2c, 3c和4进行信号表达。重组人成纤维细胞生长因子（FGF-basic）分子量为17.2 kDa，含有154个氨基酸殘基。使用无动物源试剂制造。无动物源成份。只作科研应用(RUO)。
PeproTech 100-18B Recombinant Human FGF-basic,50ug 同义词
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
PeproTech 100-18B 人重组bFGF干细胞生长因子,50ug 氨基酸序列
AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL
RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR
YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT
SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
PeproTech 100-18B Recombinant Human FGF-basic,50ug 来源: E.coli
PeproTech 100-18B Recombinant Human FGF-basic,50ug 纯度:Greater than 95% by SDS-PAGE gel and HPLC analyses.
PeproTech 100-18B Recombinant Human FGF-basic,50ug 生物活性:The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
PeproTech 100-18B Recombinant Human FGF-basic,50ug 交叉反应:Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken, Human, Horse, Bacteria, Trout, Chicken, Human + Rat, Leech, N/A, Human + Virus
PeproTech 100-18B 人重组bFGF干细胞生长因子,50ug 研究方向
血管再生/心血管, 细胞培养, FGF超家族, 炎症, 神经生物学, 增殖, 干细胞&分化, 伤口愈合
PeproTech 100-18B Recombinant Human FGF-basic,50ug 英文描述
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.